Progesterone
Composition:
Mygest 100: Each Soft Gelatin Capsule
Contains Progesterone (Micronized) 100mg USP 100mg.
Mygest
200 : Each Soft Gelatin Capsule Contains Progesterone
(Micronized) USP 200mg.
Indications:
Progesterone
softgel capsule is indicated in- 1) Maintenance of Pregnancy in cases of
Threatened / Recurrent abortion. 2) Luteal support during IUI and ART
procedures IVF-ET. 3) Luteal support in cases of proven luteal phase insufficiency.
4) Along with estrogen in post-menopausal hormone replacement therapy (HRT)
either in sequential or in continuous regimen. 5) To prevent endometrial
hyperplasia where endogenous estrogen is present. 6) As progesterone challenge
test in secondary amenorrhoea. 7) For cycle control along with estrogen
therapy. 8) Dysfunctional uterine bleeding (DUB). 9) Premenstrual tension. 10)
Endometriosis. 11) Oocyte donation programme. 12) Benign mastopathy.
Dosage
&Administration: The usual recommended dose: Progesterone 100mg/200mg
2 to 3 soft gel capsules daily by the oral or vaginal routes in divided doses.
Flexible dosage regimen can be followed depending on the indication and
requirements of patients. Maintenance of Pregnancy in cases of Threatened /
Recurrent abortion: Progesterone 200 to 400mg per day in divided doses.
In-vitro fertilization and embryo transfer: Progesterone 200mg thrice a day
from the day of embryo transfer till pregnancy is confirmed. If pregnant, it is
continued till 12’h week of pregnancy. HRT: In sequential regimen: Progesterone
200mg daily for 12 days in last 2 weeks of each therapeutic cycle. In continuous
regimen: Progesterone 100mg daily throughout the month along with estrogen.
Oocyte Donationprogramme: Progesterone 100mg twice daily from the day of
transfer till pregnancy is confirmed.This may be increased to a maximum of
600mg per day and continued till 12th week of pregnancy. Luteal support:
Progesterone 100mg thrice a day from the 17’thday of the cycle for 10 days in
induced cycle. If pregnant, it is continued till 12th week of pregnancy. Luteal
phase insufficiency: Progesterone 100mg thrice daily to be continued up to 12
weeks of pregnancy, increasing the dose by 100mg/day/week to a maximum of
600mg/day in divided doses if required. In secondary amenorrhoea: Progesterone
300mg for 10 days results in withdrawal bleeding in 80% of cases. Premenstrual syndrome:
Progesterone 100-200mg daily for 10 days from 17th to 26th day of each
menstrualcycle. Benign mastopathy: Progesterone 200-300mg for 10 days per month,
usually from 17th to 26th day of the monthly cycle. Or, as directed by the
registered physician.
Use
in Pregnancy and lactation: Pregnancy
category B. Caution should be exercised when Progesterone Capsules are
administered to a nursing woman.
Packing:
Mygest 100: Each
box contains 30's tablet in a blister pack.
Mygest 200: Each box contains 30's tablet in a blister pack.