Hydrocortisone Sodium Succinate
Composition :
Hydrason
10 Tablet: Each
tablet contains Hydrocortisone USP 10mg.
Hydrason
20 Tablet: Each
tablet contains Hydrocortisone USP 20mg.
Indications
:
It
is indicated for the treatment of 1. Endocrine Disorders: Primary or
secondary adrenocortical insufficiency, congenital adrenal hyperplasia,
nonsuppurative thyroiditis, hypercalcemia associated with cancer 2.
Rheumatic Disorders: Rheumatoid arthritis, including juvenile rheumatoid
arthritis, ankylosing spondylitis, acute and subacute bursitis, synovitis of
osteoarthritis, acute non-specific tenosynovitis, post-traumatic
osteoarthritis, psoriatic arthritis, epicondylitis, acute gouty arthritis 3.
Collagen Diseases: Systemic lupus erythematosus systemic dermatomyositis,
acute rheumatic carditis 4. Dermatologic Diseases: Bullous dermatitis
herpetiform is, severe erythema multiforme, severe seborrheic dermatitis,
exfoliative dermatitis, mycosis fungoides, pemphigus, severe psoriasis 5.
Allergic States: Seasonal or perennial allergic rhinitis, drug hypersensitivity
reactions, serum sickness, contact dermatitis, bronchial asthma, atopic
dermatitis 6. Ophthalmic Diseases: Allergic corneal marginal ulcers, herpes
zoster ophthalmicus, anterior segment inflammation, sympathetic
ophthalmia, keratitis, optic neuritis, allergic conjunctivitis
chorioretinitis, iritis and iridocyclitis 7. Respiratory Diseases: Symptomatic
sarcoidosis, berylliosis, loeffler's syndrome not manageable by other means,
fulminating or disseminated pulmonary tuberculosis when used concurrently with
appropriate antituberculous chemotherapy, aspiration pneumonitis 8.
Hematologic Disorders: Idiopathic thrombocytopenic purpura in
adults, secondary thrombocytopenia in adults, acquired (autoimmune) hemolytic
anemia, erythroblastopenia (RBC anemia), congenital (erythroid) hypoplastic
anemia 9. Neoplastic Diseases: For palliative management of: Leukemias
and lymphomas in adults, acute leukemia of childhood 10. Edematous States: To
induce a diuresis or remission of proteinuria in the nephrotic syndrome,
without uremia, of the indiopathic type or that due to lupus erythematosus 11.
Gastrointestinal Diseases: Ulcerative colitis, regional enteritis 12. Nervous System: Acute
exacerbations of multiple sclerosis etc.
Dosage
and administration : Asthma : Dosage and administration : The initial
dosage of Hydrason tablets may vary from 20 mg to 240 mg of Hydrason per day
depending on the specific disease entity being treated. In situations of less
severity lower doses will generally suffice while in selected patients higher
initial doses may be required. The initial dosage should be maintained or
adjusted until a satisfactory response is noted. If after a reasonable period
of time there is a lack of satisfactory clinical response, Hydrason should be
discontinued and the patient transferred to other appropriate therapy. IT
SHOULD BE EMPHASIZED THAT DOSAGE REQUIREMENTS ARE VARIABLE AND MUST BE
INDIVIDUALIZED ON THE BASIS OF THE DISEASE UNDER TREATMENT AND THE RESPONSE OF
THE PATIENT. After a favorable response is noted, the proper maintenance
dosage should be determined by decreasing the initial drug dosage in small
decrements at appropriate time intervals until the lowest dosage which will
maintain an adequate clinical response is reached. It should be kept in mind
that constant monitoring is needed in regard to drug dosage. Included in the
situations which may make dosage adjustments necessary are changes in clinical status
secondary to remissions or exacerbations in the disease process, the patient's
individual drug responsiveness, and the effect of patient exposure stressful
situations not directly related to the disease entity under treatment; in this
latter situation it may be necessary to increase the dosage of Hydrocortisone for
a period of time consistent with the patient's condition. If after long-term
therapy the drug is to be stopped, it is recommended that it be withdrawn
gradually. Or, as directed by the registered physician.
Use
in Pregnancy and lactation : There are no adequate and
well-controlled studies in pregnant women. Hydrocortisone should be used during
pregnancy only if the potential benefit justifies the potential risk to the
fetus. It is not known whether this drug is excreted in human milk. Caution
should be exercised when Hydrocortisone tablet is administered to a nursing
woman.
Packing
: Hydrason 10 Tablet: Each box contains 5 x10's tablets in blister pack.
Hydrason 20 Tablet: Each
box contains 3 x 10's tablets in blister pack.